HOW IS PEYRONIE´S DISEASE TREATED?

International Society for Sexual Medicine “How is Peyronie’s disease treated?” ANDROPEYRONIE (MEDICAL PEYRONIE EXTENDER)

Traction Therapy for Peyronie's Disease | ISSM
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Traction therapy following surgery for Peyronie’s disease may increase actual and perceived penile length for some men, according to new research published in the Journal of Sexual Medicine.

Peyronie’s disease, a wound-healing disorder, causes areas of hardened scar tissue called plaques to form on the penis. These plaques lead to decreased flexibility, resulting in a noticeable penile curvature during erection. Some men with Peyronie’s disease experience pain and are unable to have intercourse.

Surgery is one treatment option. Two types of surgeries pertain to this study. The first is called tunica albuginea plication (TAP) and involves stitching the area on the opposite side of the plaques to straighten the curvature. The other procedure is partial plaque excision and grafting (PEG), in which a surgeon makes an incision in the plaque and fills it with graft material.

One common complication of surgery for Peyronie’s disease is penile shortening, which can be a serious concern.

In this study, American researchers from Rush University Medical Center in Chicago worked with four groups of men. (A total of 134 men participated.) Two groups had TAP surgery, the other two had PEG procedures. For each type of surgery, one group had traction therapy and the other did not.

Traction therapy ( ANDROPEYRONIE ) involved wearing a traction device on the penis for a recommended 2–6 hours each day starting 3–4 weeks after surgery. From that point, patients were advised to use the device for three months. The goal of traction therapy (ANDROPEYRONIE) was to keep the penis straight as it healed and prevent length loss.

Stretched penile length measurements were taken before and after treatment. In addition, all men were mailed a questionnaire that asked about their perceptions of penile length change and their pre- and post-surgery satisfaction.

For the men who underwent TAP :

• The mean length change was 0.85 cm.

• 68% perceived erect length gain.

• 0% perceived erect length loss.

• 32% perceived no change in erect length.

For men who underwent TAP without traction therapy:

• The mean length change was -0.53 cm.

• 7% perceived erect length gain.

• 79% perceived erect length loss.

• 14% perceived no change in erect length.

For men who underwent PEG and traction therapy ( ANDROPEYRONIE ):

• The mean length change for was 1.48 cm.

• 47% perceived erect length gain.

• 0% perceived erect length loss.

• 53% perceived no change in erect length.

For men who underwent PEG without traction therapy:

• The mean length change was 0.24 cm.

• 14% perceived erect length gain.

• 57% perceived erect length loss.

• 29% perceived no change in erect length.

Overall, 69% of all participants were satisfied with their surgical outcome.

There were no complications or changes in penile sensation associated with traction therapy.

The researchers concluded that traction therapy can preserve some measured and perceived penile length after surgery for Peyronie’s disease. However, because of the psychological implications of penile length and outcome satisfaction, it is important for men to have realistic expectations before they have surgery.

Resources

International Society for Sexual Medicine

“How is Peyronie’s disease treated?”

http://www.issm.info/sexual-health-qa/how-is-peyronies-disease-treated

Journal of Sexual Medicine

Rybak, James, MD, et al.

“A Retrospective Comparative Study of Traction Therapy vs. No Traction Following Tunica Albuginea Plication or Partial Excision and Grafting for Peyronie’s Disease: Measured Lengths and Patient Perceptions”

(Full-text. First published online: August 17, 2012)

http://onlinelibrary.wiley.com/doi/10.1111/j.1743-6109.2012.02849.x/abstract

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andropenis penile traction devicePenile Traction Therapy For Treatment Of Peyronie's Illness: A Single-Center Pilot Research Study
Penile Traction Therapy For Treatment Of Peyronie's Disease: A Single-Center Pilot StudyPublished Saturday 10 May 2018 Adapted Media Release
UroToday.com - The pilot research study as well as recurring scientific experience indicates the crucial relevance of individual conformity if an enhanced result is to be gotten from use of the andropenis penile traction tool While of the research, other patients at the research study website were being treated with intralesional injections, an extra hostile treatment modality, with the expectation that remarkable results would certainly be accomplished. It was, actually, noted that a larger portion of the study people were accomplishing far better outcomes on grip alone. It was presumed that patient compliance was the figuring out factor. An absolute minimum of 2 hours utilize per day, four to six hours being excellent, are called for to produce favorable results over a 4 to 6 month period with traction treatment (andropenis). This is challenging for several people to achieve, as are numerous therapies calling for devoted self-monitored compliance. In making the research study protocol, it was determined to include once a week calls to each subject. These telephone calls were seemingly made to urge conformity, look at development, to provide early recognition of concerns and also to remind subjects of visit dates. The calls also satisfied of inspiring the subject and of producing a feeling of continuous rate of interest as well as support on the part of the researchers. This, it was felt, made a significant distinction in the level of subject compliance, and therefore the favorable end result achieved by all research topics.
andropenis penis extender tool.Considering that conclusion of the study in November of 2017, Dr. Levine has actually continued to focus interest on the possibility of the andropenis Extender as component of combination therapies utilizing intralesional Verapamil as well as dental representatives. It is felt that, with proper patient compliance, the combination of penile grip therapy as well as intralesional medicines may supply both sped up as well as boosted results for Peyronie's clients. Data gathered by Dr. Levine currently is not sufficient to support certified statements about results, however present methods remain to check out the harmonies in between grip forces and the chemical results of Verapamil.
Additionally, Levine as well as Newell, with other scientists, are creating studies on the capacity for the device to aid people gain back penile length adhering to loss of penile length prior to, and adhering to, radical prostatectomy, as well as prior to implantation of penile prosthetics. While the emphasis of the cited study was decrease of penile curvatures, it was likewise noted that individuals also accomplished gains in size.

This may indicate that the device can help patients restore all or part of penile length lost as a result of penile atrophy following prolonged erectile dysfunction (ED).

  Written by Laurence A. Levine, MD, Mark Newell, PhD, Frederick L. Taylor ,MD, as part of Beyond the Abstract on UroToday.com.

Want A Longer Penis? Traction (andropenis) Beats Surgery, Say Researchers

 

Men who want surgery to increase the length of their penis should try non-invasive methods like penile traction device (andropenis) or  extenders first, and in some cases, even try therapy to make them feel more confident about their bodies, said Italian urologists  in   a paper published in the April print issue of the British Journal of Urology International.

 Marco Orderda and Paolo Gontero of the University of Turin carried out a research review and concluded that penile extender andropenis   were more effective than other non-invasive methods like vacuum devices, exercises and botox injections.

 They also noted that surgery was not necessarily the perfect solution that some might assume it to be.

 Gontero, an Associate urology Professor, told the media:

 "Based on current evidence, we suggest that penile extender (andropenis), not surgery, should be the first-line treatment for men seeking a   penile lengthening procedure."

 "Surgery is characterised by a risk of complications and unwanted outcomes and lack of consensus among the medical profession   on the indications for surgery and the techniques used. That is why a non-invasive technique is preferable," said   Gontero.

 In some cases, psychological satisfaction is often just as important as physical changes, Orderda and Gontero noted.

 Gontero said urologists are often approached by men worried about the size of their penis, even though in most cases, the penis is   of normal size.

 But there are some conditions such as Peyronie's disease and congenital abnormalities that can leave a man with a shorter than   normal penis, as can surgical procedures like radical prostatectomy for men with prostate cancer.  Lack of skin due to chronic   inflammation or aggressive circumcision can also make the penis appear smaller.

 And another condition is "hidden penis", often seen in obese older men whose belly fat and skin overlies the penis.

 According to most of the studies that they reviewed, a penis was considered normal if its length when flaccid was more than 4   cm, and when erect, was more than 7.5 cm, but this also depended on height and BMI.  The length was measured along the dorsal   or upper side.

 Gontero said that no studies have yet compared surgical and non-invasive methods of increasing penis length (andropenis).

 "However our review suggests that penile extenders represent an effective and durable method of penile lengthening, capable of   elongating the penis by an average of 1.8cm with minimal side effects. This compares favourably with surgery, which is much   more invasive for the patient," he added.

  Gontero and Oderda reviewed five evidence-based studies of penile surgery on a total of 121 men, and six evidence-based studies of non-surgical interventions covering a total of 109 men, 72 of whom used the penile extenders.    All the studies were published between 2000 and 2009.

 They found that surgical procedures resulted in average flaccid length increases of 1.3 to 2.5 cm, while studies of three types of   penile extender (andropenis) resulted in average flaccid length increases of 0.5 to 2.3 cm.

 Penile extender (andropenis) usually require the penis being in traction for several hours a day for several months, and the researchers wondered whether the gains were worth it.

 A small number of the men who used penile extenders reported experiencing bruising, temporary discoloration, pain and   itching.

 One study that looked at the long term effects of repeated vacuum treatment in 37 men found no significant change in penis   length after six months, although it reported a degree of psychological satisfaction for some men.  One man reported experiencing   numbness, and another man had a haematoma (blood under the tissue).

 Another study they reviewed showed that botox may have a temporary effect in increasing flaccid length and decreasing penile   retraction, while a further study suggested that using penoscrotal rings with an erectile dysfunction drug could help anxious men   maintain an erection, but the reviewers could only find two case reports that measured how effective these devices  were.

 Ordeda and Gontero noted that despite the fact the idea appeals to a lot of men, and that it is widely discussed on the internet,   probably because it is cheap and involves  no invasive procedures, there is no evidence that exercises can help a man lengthen his   penis.

 Many men who feel their penis is too small are often surprised to discover that it is in the normal size range.  This means there is a   role for therapy in helping these patients, said the reviewers, who recommended they try cognitive behavioral therapy to improve  their perception of their body image.

  Written by: Catharine Paddock, PhD

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Penile Traction Therapy (andropeyronie): Benefits for Men with Peyronie’s Disease

Penile Traction Therapy (andropeyronie): Benefits for Men with Peyronie’s Disease 

andropeyronie extender

Penile traction therapy refers to mechanical stretching of the penis.   To help with the task, numerous devices designed to stretch the penis and keep it stretched for prolonged periods of time have been produced.

Penile traction devices are sold without a prescription.

What is Penile Traction used for?

Penile traction therapy is used for a number of reasons.

Penile traction therapy has been shown to increase penile length  3-5 cm on average.  Because penile shortening is a significant problem for men with Peyronie’s disease, penile traction therapy can potentially prevent penile shortening or reverse it to some extent in some men.

Penile traction has also shown to help with straightening penile curvature caused by Peyronie’s disease.  It is typically used in combination with penile plaque injection therapy.

Is there a Rational Reason for Using Penile Traction Therapy?

It is well known that many biological process can occur in response to cell stretching.  Mechanoreceptors on the wall of many cells can get activated and can lead to physiological processes.  In the case of Peyronie’s disease there is evidence that activation of mechanoreceptors can lead to scar re-organization.

How Effective Is Penile Traction for Treatment of Men with Peyronie’s Disease

Multiple studies have shown a benefit in gaining of penile length with the use of penile traction devices. It is important to note that success of treatment depends on duration and frequency of use. Typically use of penile traction for 6-7 hours a day for at least 6 months is required to achieve a benefit.

Studies also show benefit when it comes to penile curvature.

How to Use Penile Traction?

Studies show that penile traction is only beneficial with dedicated use. Men who benefit from penile traction use it 4-8 hours a day for 6 months before they see improvements.

When to Use Penile Traction?

I advise that penile traction therapy is initiated early as soon as signs and symptoms of Peyronie’s disease are identified and diagnosed.   The goal of penile traction therapy is three-fold:

1. Prevent worsening of symptoms, in particular prevent penile shortening that affects many men with Peyronie’s disease.
2. Reverse penile shortening that has occurred
3. Prevent and reverse penile curvature

andropeyronie extender

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Novel Peyronie’s Disease Treatment Shows Efficacy

 

Novel Peyronie’s Disease Treatment Shows Efficacy

Novel Peyronie’s Disease Treatment Shows Efficacy, andropeyronie penis extender therapy peyronie

Novel Peyronie’s Disease Treatment Shows Efficacy

https://www.renalandurologynews.com/erectile-dysfunction-ed/novel-peyronies-disease-treatment-shows-efficacy/article/342089/

Penile traction therapy PTT (andropeyronie)is an effective treatment for the acute phase of Peyronie’s disease (PD), Spanish researchers reported in The Journal of Sexual Medicine(2014; 11:506-- 515).

Juan Martínez-Salamanca, MD, PhD, of the Department of Urology at the Autonomous University of Madrid as well as colleagues examined 55 clients who underwent PTT, a novel penile extender device therapy (andropeyronie), for 6 months for severe phase (AP) of Peyronie's. These people were compared to 41 patients in the intense stage of Peyronie's condition that received no active treatment.

From standard, imply curvature in individuals treated with PTT had lowered from 33 ° to 15 ° at 6 months as well as 13 ° at 9 months, with a mean reduction of 20 °. Erectile feature as well as firmness improved substantially, and also the percentage of people unable to attain infiltration reduced from 62% to 20%.

The requirement for surgical procedure was decreased in 40% of people who would or else have actually been eligible, and the complexity of surgeries was more streamlined in 1 out of 3 people. PTT was related to the removal of sonographic plaques in 48% of clients treated.

The non-active therapy team had a considerable increase in penile defect, where function and also firmness intensified as well as stretched flaccid penile size had reduced.

"PTT appears an efficient therapy for the AP of PD in regards to pain decrease, penile curvature decline, as well as improvement in sex-related function," the writers concluded.

Pathophysiological Aspects of Peyronie’s Disease:

Pathophysiological Aspects of Peyronie’s Disease: Role of Free Radicals, Rationale, and Therapeutic Implications for Antioxidant Treatment — Literature

Abstract

Peyronie's illness (PD) is a chronic swelling of tunica albuginea of the corpora cavernosa that creates an inelastic plaque causing penis contortion. Although its etiology is not totally known, there is general consensus that PD is genetically sent and also secondary to penile trauma. In recent years, many researches demonstrated the function played by oxidative anxiety in PD pathogenesis, and also various other research studies have described successful use antioxidants in PD treatment. Oxidative stress and anxiety is an integral component of this disease, affecting its development. In the early stages of PD, the inflammatory infiltrate cells create high quantities of totally free radicals and also proinflammatory and profibrotic cytokines, with consequent activation of transcription aspect NF-κB. While conventional treatments generally used in the beginning of PD include dental materials (Potaba, tamoxifen, colchicine, and vitamin E), intralesional therapy (verapamil, interferon, steroids, as well as much more lately collagenase clostridium histolyticum-Xiaflex), as well as neighborhood physical treatment and also penile extender (andropeyronie), the substantial results gotten by arising treatments with the antioxidants pointed out in this post recommend these therapeutic agents conflict at a number of levels with the disease's pathogenetic devices. Antioxidants therapy results are fascinating forever medical method as well as additionally confirm the fundamental role played by oxidative stress and anxiety in PD. Gianni Paulis,1,2 Gennaro Romano,3 Luca Paulis,4 as well as Davide Barletta5

1.1. Premises of Microscopic and also Functional Anatomy

The tunica albuginea of the corpora cavernosa is comprised of both collagen fibers (the bulk) as well as flexible fibers. Whereas collagen fibers have greater resistance to grip as well as are inelastic, flexible fibers can be expanded approximately 150% of their typical length [18] With no flexible fibers in the tunica albuginea, the penis would not be able to expand in length and also dimension throughout erection. In typical conditions as well as in the absence of illness, the flexible fibers along the penile shaft, within the tunica albuginea, appear as a net interwoven with collagen fibers. Nonetheless, in the penile crura and distal component of the corpora cavernosa (peak), the tunica albuginea is just or practically specifically made up of collagen fibers [18, 19] Hence, any type of neighborhood adjustment in flexible fiber content can cause penile deformation.

The purpose of this short article is to clarify and also explain the significant function of the oxidative tension in PD pathogenesis; the various other vital purpose of the article is to clarify the resulting role of antioxidants in PD therapy.

In 2012, a study analyzed PTX efficacy in 74 PD people using a combined therapy which included dental PTX (400 mg/three times daily) associated with oral L-arginine (1 g/twice daily) and verapamil shots (12 in overall, every 2 weeks). Seventy-four PD individuals were divided into 2 treatment teams: team I (39 people), verapamil shots + dental treatment (L-arginine + PTX) + everyday penile grip therapy PTT (andropeyronie) for 6 months.

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